Objective: To explore the clinicopathological characteristics of spiradenoma (SA), and make exact diagnosis and differential diagnosis of this disease. Methods: The clinical and pathological data of 11 patients with spiradenoma in the First Affiliated Hospital of Jinan University from 2013 to 2022 were retrospectively analyzed, and combined with the review of literatures. Results: Among the 11 patients with spiroadenomas, 6 cases were male and 5 were female; the age ranged from 19 to 70 years old, with an average age of 41 years; Spiradenomas are more common in the trunk and limbs. At low-power microscope, the tumor mass with capsule in the dermis. Under a high-power microscope, the tumor is usually composed of two types of cells, which are the marginal small basaloid cells with dark staining and central larger cells with a pale and acidophilic nucleus. Other morphological structures included 2 cases of cystic solid and cylindroma respectively. Immunohistochemistry showed that epithelial and myoepithelial differentiation. Conclusion: Spiradenoma often occurs subcutaneously and requires histopathological diagnosis to avoid misdiagnosis. Its biological behavior is benign and its prognosis is good. But malignant transformation should be considered in some case with long course or relapses. SA is rare in clinical and is prone to misdiagnosis or missed diagnosis. This study summarizes the clinilcopathological characteristics of SA, providing reference for future clinical diagnosis and treatment.
| Published in | American Journal of Clinical and Experimental Medicine (Volume 12, Issue 2) |
| DOI | 10.11648/j.ajcem.20241202.11 |
| Page(s) | 8-12 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Spiradenoma, Pathological Features, Differential Diagnosis
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APA Style
Tian, Q., Hu, Y., Lu, Y. (2024). Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor. American Journal of Clinical and Experimental Medicine, 12(2), 8-12. https://doi.org/10.11648/j.ajcem.20241202.11
ACS Style
Tian, Q.; Hu, Y.; Lu, Y. Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor. Am. J. Clin. Exp. Med. 2024, 12(2), 8-12. doi: 10.11648/j.ajcem.20241202.11
AMA Style
Tian Q, Hu Y, Lu Y. Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor. Am J Clin Exp Med. 2024;12(2):8-12. doi: 10.11648/j.ajcem.20241202.11
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Download@article{10.11648/j.ajcem.20241202.11,
author = {Qianyuan Tian and Yunfeng Hu and Yuanzhi Lu},
title = {Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor
},
journal = {American Journal of Clinical and Experimental Medicine},
volume = {12},
number = {2},
pages = {8-12},
doi = {10.11648/j.ajcem.20241202.11},
url = {https://doi.org/10.11648/j.ajcem.20241202.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20241202.11},
abstract = {Objective: To explore the clinicopathological characteristics of spiradenoma (SA), and make exact diagnosis and differential diagnosis of this disease. Methods: The clinical and pathological data of 11 patients with spiradenoma in the First Affiliated Hospital of Jinan University from 2013 to 2022 were retrospectively analyzed, and combined with the review of literatures. Results: Among the 11 patients with spiroadenomas, 6 cases were male and 5 were female; the age ranged from 19 to 70 years old, with an average age of 41 years; Spiradenomas are more common in the trunk and limbs. At low-power microscope, the tumor mass with capsule in the dermis. Under a high-power microscope, the tumor is usually composed of two types of cells, which are the marginal small basaloid cells with dark staining and central larger cells with a pale and acidophilic nucleus. Other morphological structures included 2 cases of cystic solid and cylindroma respectively. Immunohistochemistry showed that epithelial and myoepithelial differentiation. Conclusion: Spiradenoma often occurs subcutaneously and requires histopathological diagnosis to avoid misdiagnosis. Its biological behavior is benign and its prognosis is good. But malignant transformation should be considered in some case with long course or relapses. SA is rare in clinical and is prone to misdiagnosis or missed diagnosis. This study summarizes the clinilcopathological characteristics of SA, providing reference for future clinical diagnosis and treatment.
},
year = {2024}
}
TY - JOUR T1 - Clinicopathological Characteristics of 11 Cases with Spiradenoma: A Rare Adnexal Tumor AU - Qianyuan Tian AU - Yunfeng Hu AU - Yuanzhi Lu Y1 - 2024/04/11 PY - 2024 N1 - https://doi.org/10.11648/j.ajcem.20241202.11 DO - 10.11648/j.ajcem.20241202.11 T2 - American Journal of Clinical and Experimental Medicine JF - American Journal of Clinical and Experimental Medicine JO - American Journal of Clinical and Experimental Medicine SP - 8 EP - 12 PB - Science Publishing Group SN - 2330-8133 UR - https://doi.org/10.11648/j.ajcem.20241202.11 AB - Objective: To explore the clinicopathological characteristics of spiradenoma (SA), and make exact diagnosis and differential diagnosis of this disease. Methods: The clinical and pathological data of 11 patients with spiradenoma in the First Affiliated Hospital of Jinan University from 2013 to 2022 were retrospectively analyzed, and combined with the review of literatures. Results: Among the 11 patients with spiroadenomas, 6 cases were male and 5 were female; the age ranged from 19 to 70 years old, with an average age of 41 years; Spiradenomas are more common in the trunk and limbs. At low-power microscope, the tumor mass with capsule in the dermis. Under a high-power microscope, the tumor is usually composed of two types of cells, which are the marginal small basaloid cells with dark staining and central larger cells with a pale and acidophilic nucleus. Other morphological structures included 2 cases of cystic solid and cylindroma respectively. Immunohistochemistry showed that epithelial and myoepithelial differentiation. Conclusion: Spiradenoma often occurs subcutaneously and requires histopathological diagnosis to avoid misdiagnosis. Its biological behavior is benign and its prognosis is good. But malignant transformation should be considered in some case with long course or relapses. SA is rare in clinical and is prone to misdiagnosis or missed diagnosis. This study summarizes the clinilcopathological characteristics of SA, providing reference for future clinical diagnosis and treatment. VL - 12 IS - 2 ER -
Department of Dermatology, First Affiliated Hospital of Ji’nan University, Guangzhou, China
Department of Dermatology, First Affiliated Hospital of Ji’nan University, Guangzhou, China
Department of Pathology, First Affiliated Hospital of Ji’nan University, Guangzhou, China
